NBC sets premiere date for “Do No Harm” drama












LOS ANGELES (TheWrap.com) – NBC will premiere its new drama “Do No Harm” at 10 p.m. on January 31, NBC Entertainment chairman Robert Greenblatt said Friday.


The premiere date takes advantage of the one-hour series finale of “30 Rock,” which will air at 8 p.m. on that same night.












“Do No Harm” stars “Rescue Me” alum Steven Pasquale as Dr. Jason Cole, a neurosurgeon whose life is going swimmingly until his dangerous alter-ego emerges, hell-bent on creating havoc on Cole and those around him.


“January 31 will be a special night as one classic series will mark its finale with a great hour-long send-off episode while a promising new drama will make its debut on Thursdays,” Greenblatt said. “‘30 Rock’ is acclaimed as a legendary comedy and we will see a truly memorable and fitting last episode. In ‘Do No Harm,’ viewers will have a unique new dramatic storyline with an exciting new star in Steven Pasquale that takes them into dark and uncharted territory.”


To accommodate “Do No Harm,” “Rock Center With Brian Williams” will move to Fridays at 10 p.m., following “Dateline,” beginning February 8.


TV News Headlines – Yahoo! News


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Unboxed: Stand-Up Desks Gaining Favor in the Workplace


THE health studies that conclude that people should sit less, and get up and move around more, have always struck me as fitting into the “well, duh” category.


But a closer look at the accumulating research on sitting reveals something more intriguing, and disturbing: the health hazards of sitting for long stretches are significant even for people who are quite active when they’re not sitting down. That point was reiterated recently in two studies, published in The British Journal of Sports Medicine and in Diabetologia, a journal of the European Association for the Study of Diabetes.


Suppose you stick to a five-times-a-week gym regimen, as I do, and have put in a lifetime of hard cardio exercise, and have a resting heart rate that’s a significant fraction below the norm. That doesn’t inoculate you, apparently, from the perils of sitting.


The research comes more from observing the health results of people’s behavior than from discovering the biological and genetic triggers that may be associated with extended sitting. Still, scientists have determined that after an hour or more of sitting, the production of enzymes that burn fat in the body declines by as much as 90 percent. Extended sitting, they add, slows the body’s metabolism of glucose and lowers the levels of good (HDL) cholesterol in the blood. Those are risk factors toward developing heart disease and Type 2 diabetes.


“The science is still evolving, but we believe that sitting is harmful in itself,” says Dr. Toni Yancey, a professor of health services at the University of California, Los Angeles.


Yet many of us still spend long hours each day sitting in front of a computer.


The good news is that when creative capitalism is working as it should, problems open the door to opportunity. New knowledge spreads, attitudes shift, consumer demand emerges and companies and entrepreneurs develop new products. That process is under way, addressing what might be called the sitting crisis. The results have been workstations that allow modern information workers to stand, even walk, while toiling at a keyboard.


Dr. Yancey goes further. She has a treadmill desk in the office and works on her recumbent bike at home.


If there is a movement toward ergonomic diversity and upright work in the information age, it will also be a return to the past. Today, the diligent worker tends to be defined as a person who puts in long hours crouched in front of a screen. But in the 19th and early 20th centuries, office workers, like clerks, accountants and managers, mostly stood. Sitting was slacking. And if you stand at work today, you join a distinguished lineage — Leonardo da Vinci, Ben Franklin, Winston Churchill, Vladimir Nabokov and, according to a recent profile in The New York Times, Philip Roth.


DR. JAMES A. LEVINE of the Mayo Clinic is a leading researcher in the field of inactivity studies. When he began his research 15 years ago, he says, it was seen as a novelty.


“But it’s totally mainstream now,” he says. “There’s been an explosion of research in this area, because the health care cost implications are so enormous.”


Steelcase, the big maker of office furniture, has seen a similar trend in the emerging marketplace for adjustable workstations, which allow workers to sit or stand during the day, and for workstations with a treadmill underneath for walking. (Its treadmill model was inspired by Dr. Levine, who built his own and shared his research with Steelcase.)


The company offered its first models of height-adjustable desks in 2004. In the last five years, sales of its lines of adjustable desks and the treadmill desk have surged fivefold, to more than $40 million. Its models for stand-up work range from about $1,600 to more than $4,000 for a desk that includes an actual treadmill. Corporate customers include Chevron, Intel, Allstate, Boeing, Apple and Google.


“It started out very small, but it’s not a niche market anymore,” says Allan Smith, vice president for product marketing at Steelcase.


The Steelcase offerings are the Mercedes-Benzes and Cadillacs of upright workstations, but there are plenty of Chevys as well, especially from small, entrepreneurial companies.


In 2009, Daniel Sharkey was laid off as a plant manager of a tool-and-die factory, after nearly 30 years with the company. A garage tinkerer, Mr. Sharkey had designed his own adjustable desk for standing. On a whim, he called it the kangaroo desk, because “it holds things, and goes up and down.” He says that when he lost his job, his wife, Kathy, told him, “People think that kangaroo thing is pretty neat.”


Today, Mr. Sharkey’s company, Ergo Desktop, employs 16 people at its 8,000-square-foot assembly factory in Celina, Ohio. Sales of its several models, priced from $260 to $600, have quadrupled in the last year, and it now ships tens of thousands of workstations a year.


Steve Bordley of Scottsdale, Ariz., also designed a solution for himself that became a full-time business. After a leg injury left him unable to run, he gained weight. So he fixed up a desktop that could be mounted on a treadmill he already owned. He walked slowly on the treadmill while making phone calls and working on a computer. In six weeks, Mr. Bordley says, he lost 25 pounds and his nagging back pain vanished.


He quit the commercial real estate business and founded TrekDesk in 2007. He began shipping his desk the next year. (The treadmill must be supplied by the user.) Sales have grown tenfold from 2008, with several thousand of the desks, priced at $479, now sold annually.


“It’s gone from being treated as a laughingstock to a product that many people find genuinely interesting,” Mr. Bordley says.


There is also a growing collection of do-it-yourself solutions for stand-up work. Many are posted on Web sites like howtogeek.com, and freely shared like recipes. For example, Colin Nederkoorn, chief executive of an e-mail marketing start-up, Customer.io, has posted one such design on his blog. Such setups can cost as little as $30 or even less, if cobbled together with available materials.


UPRIGHT workstations were hailed recently by no less a trend spotter of modern work habits and gadgetry than Wired magazine. In its October issue, it chose “Get a Standing Desk” as one of its “18 Data-Driven Ways to Be Happier, Healthier and Even a Little Smarter.”


The magazine has kept tabs on the evolving standing-desk research and marketplace, and several staff members have become converts themselves in the last few months.


“And we’re all universally happy about it,” Thomas Goetz, Wired’s executive editor, wrote in an e-mail — sent from his new standing desk.


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L.A. County seeing high-risk offenders entering its probation system









One year into California's state prison realignment program, Los Angeles County is seeing an unexpected number of high-risk offenders coming into its probation system, including some with a history of severe mental illness.


It remains unclear whether realignment — which shifted responsibility for some nonviolent offenders from prisons to county jails and from state parole to county probation — is having an effect on crime rates. But a report by a county advisory body found that a majority of state prison inmates who have been released to county probation are at a high risk of reoffending.


In the first year of the new system, which took effect in October 2011, 11,136 offenders were released from state prison to Los Angeles County probation. Of those who reported to probation for assessment, 59% were classed as high risk, 40% as medium risk and only 1% as low risk.





The department uses probationers' criminal history and other factors to determine the risk that they will commit new crimes and the resources required to supervise them.


Deputy Chief Reaver Bingham said the department originally projected that 50% of the offenders coming out of state prison would fall into the high-risk category.


And a handful of people previously classified as mentally disordered offenders — people considered dangerous because of mental illness — were downgraded or "decertified" while in state hospitals, making them eligible for county supervision, according to the report issued Thursday by the Countywide Criminal Justice Coordination Committee.


County officials said that runs contrary to the spirit of realignment, which was pitched as a money-saving measure for the state that would transfer low-level offenders to less costly county supervision. The committee's report said the decertified mentally disordered offenders "present high public safety risk, present significant placement issues, and consume high levels of resources."


Jeffrey Callison, a spokesman with the state corrections department, said the courts, not the department, determine who is decertified and that under the current law, people not classified as mentally disordered who are eligible for realignment are required to go to county supervision.


"It's not for me to say that a given county does or doesn't have the resources to supervise a person who has been decertified," he said.


The committee's report recommended that the county seek legislation to shift back to the state responsibility for probationers formerly designated as mentally disordered offenders as well as "medically fragile" people and prisoners serving long sentences in county jail.


abby.sewell@latimes.com





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Only in Vegas: Sprinting Santas and Run-Through Weddings











LAS VEGAS — Only in Sin City would the sight of 8,000 Santas running amok through the streets not raise an eyebrow. Even the Elvis Santas barely drew second glances in this town, where the King is as common as bad buffets and bad judgment.



But such things are par for the course when you’re running in a city where everything is just a bit more … weird, including the sports. The insanity returns this weekend with a zany fitness double feature that brings the 8th annual Great Santa Run and the Rock n’ Roll Las Vegas Marathon to town.


Part of what makes the Santa fun run so, well, fun, is everyone gets a brand-new five-piece Santa suit. I caught the action a few years back and seeing these photos still makes me smile.


As silly as that is — and it’s pretty freakin’ silly — it’s but a warmup to the Rock n’ Roll marathon. These things are held in cities around the world and they’re always lots of fun — well, fun if you’re capable of running 26.2 miles without dying — but the Vegas version is just a bit more so.


It isn’t the 40,000 people running down Las Vegas boulevard, or the live music, or even the celebrity impersonators — is that Celine Dion? — huffing and puffing down the Strip.


No, what makes this a distinctly Vegas experience is the run-through wedding service. That’s right. You and your dearly beloved can take a brief detour from the course and get hitched outside the Paris Las Vegas hotel and casino. Talk about an endurance race.


I’m still awaiting the addition of a run-through divorce court. Maybe next year.


All photos: Sol Neelman/Wired




Sol Neelman photographs the wonderful world of weird sports, from dog surfing to outhouse racing to underwater hockey. His book, "Weird Sports," is available now. If you've got a goofy game or silly sport you think he should cover, drop him a line.

Read more by Sol Neelman

Follow @solneelman on Twitter.



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“iCarly” and “Victorious” spinoff gets greenlight from Nickelodeon












LOS ANGELES (TheWrap.com) – Tweens of the world, rejoice: “iCarly” may be relegated to the dustbin of TV-programming history, but a part of it will live on.


Nickelodeon has greenlit “Sam & Cat,” a hybrid spinoff of “iCarly” – which ended its run last week – and the Nickelodeon seriesVictorious.”












The series – from “iCarly” and “Victorious” creator Dan Schneider – will star Jennette McCurdy (who played Sam Puckett on “iCarly”) and Ariana Grande (perhaps better known as Cat Valentine to “Victorious” viewers). Both will reprise theo become teen entrepreneurs by starting their own after-school babysitting business.”


The 20-episode first season of “Sam & Cat” will premiere next year; production will begin in January in Los Angeles.


“Jennette and Ariana are adored by our audience, and it’s great to unite these talented actresses in this hilarious new comedy from Dan Schneider,” Nickelodeon’s president of content development and production Russell Hicks said. “This show promises to deliver on what our audience loves most about these two favorite characters – laugh-out-loud humor and non-stop adventure, and is sure to be a compelling new chapter for our new comedic duo.”


The “iCarly” series finale last week drew 6.4 million viewers.


TV News Headlines – Yahoo! News


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Prop. 8 supporters, opponents await Supreme Court decision









At San Francisco City Hall, officials are awaiting their moment in history, but they just don't know when it will come.


In the complex calculus of gay marriage in California, weddings could become legal within days. So City Hall is preparing for a possible crush of same-sex couples seeking marriage licenses and making contingency plans for demonstrations.


But it is also possible that this preparation is for naught and the future of same-sex unions will remain up in the air for months or longer.





CHRONOLOGY: Gay marriage in the U.S.


The U.S. Supreme Court is poised to take up the issue of gay marriage in California as soon as Friday morning. The moment has prompted nervous debate within the gay-rights movement about the best path to achieve gay marriage.


If the justices opt not to hear the Proposition 8 case, then a federal appeals court ruling that found the 2008 state ballot measure banning same-sex marriage unconstitutional would stand, clearing the way for marriages to begin. If the justices take up the case, a ruling would not come until next year and gay marriage would remain on hold until then, or longer depending on how the court rules.


Were the high court to decide to rule on Hollingsworth vs. Perry, it could lead to a historic victory legalizing same-sex marriage nationwide. But gay activists are well aware that the court could rule against them and throw the movement back at a time when same-sex marriage has seen a series of election victories at the state level.


Opponents of gay marriage, by contrast, are eager for the Supreme Court to weigh in and are hoping it will block the growing legalization of same-sex unions.


"This claim that somehow hidden within the U.S. Constitution is this right to redefine marriage is just false," said Brian Brown, the president of the National Organization for Marriage.


Jim Campbell, legal counsel for Alliance Defending Freedom, which represents the official proponents of Proposition 8, agreed, and said he hoped the high court would conclude "that defining marriage as the union of a man and a woman is constitutional."


It's been four years since California voters approved a ban on gay marriage. During that time, several more states have legalized gay marriage; it is now legal in nine states and the District of Columbia. Many gay-rights activists in California feel left behind and eager for the state to resume marriages. The question is: How best to make it happen?


Jeffrey J. Zarrillo, who with his partner is a plaintiff in the federal suit now before the court, wants the high court to hear the case, which he is confident of winning. "This case is important in all 50 states, not just California," said Zarrillo, 39, a Burbank resident.


TIMELINE: Gay marriage since 2000


But Kate Kendell, executive director of the National Center for Lesbian Rights, is one of the voices of caution. "Anything is possible with any court," she warned, and legal scholars don't give a win in the case "the best odds."


For that reason, Kendell said she hopes the court doesn't take the case. That would still "put a grave marker on top of Proposition 8 once and for all and allow California couples to marry." Recent studies from the Williams Institute at UCLA law school, a think tank on sexual orientation policy, found that there are nearly 100,000 same-sex couples living in California, and that 24,000 would marry in the next three years if they had the opportunity to do so.


The long years of litigation also have left some gays and lesbians impatient and frustrated and questioning whether the courts remain their best forum for achieving marriage equality. Given the victories on election night, some believe that the ballot box, not the legal system, may now be the answer.


"There are definitely divisions in terms of people's views," said Gary Gates, a researcher at the Williams Institute. Some "say if this case hadn't come up, and we had put it on the ballot … we might have had marriage back."


The divergence of opinion echoes back to the days when the historic federal lawsuit was first filed in 2009. At the time, many gay-rights groups opposed going into federal court, fearing a setback at the U.S. Supreme Court. They preferred to tackle marriage rights state by state.


CHRONOLOGY: Gay marriage in the U.S.


But with voters passing marriage bans across the country, a political strategist in Los Angeles, Chad Griffin, hired a top-notch legal team to sue to overturn Proposition 8 in federal district court in San Francisco. Both the trial court and the U.S. 9th Circuit Court of Appeals ruled against California's marriage ban.





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New Camera Snaps All-Sky Auroras in Full Color











Capturing a multicolored, all-sky image of the auroras that decorate Earth’s polar skies is now possible.


Normally, studying these shimmering phenomena means taking multiple images of an aurora, using different filters that block or image different wavelengths. Now, a camera with tunable liquid crystal filters can capture many colors at once, a team of space-weather researchers reports Nov. 29 in Optics Express.


Called NORUSCA II, the camera also takes pictures of the entire sky. Scientists are hoping that such precision aurora-imaging will help them better understand and classify the celestial light shows.


The team tested the sky-gazing camera at the Kjell Henriksen Observatory in Svalbard, Norway, during the auroral season of 2011 and 2012. On Jan. 24, 2012, an enormous solar flare flung a blob of charged particles in Earth’s direction. The skies over Svalbard lit up as the particles struck Earth’s atmosphere, producing a bright green aurora and intense geomagnetic storm.



Charged particles colliding with different gases in Earth’s atmosphere produce the multicolored auroras. For example, oxygen atoms can glow green or red, depending on their altitude. Hydrogen and helium high in the ionosphere can produce shimmering blue or purple. Nitrogen? Red, violet, or blue.


The new camera captured these swirling lights using many different wavelength channels; individual frames from the Jan. 24 event have been stitched together in the video above. And the camera is sensitive enough to see daytime auroras, like the reddish lights flickering across the sky on Dec. 29, 2011 (video below).



Videos: Optics Express, Vol. 20, Issue 25.









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Actor who apparently killed landlady not on drugs












LOS ANGELES (AP) — An autopsy report shows no drugs were detected in the body of a former “Sons of Anarchy” actor who police say killed his landlady and then fell to his death.


Toxicology results on Johnny Lewis found no traces of cocaine, alcohol, marijuana or any other types of drugs in the actor’s system. Officials checked for anti-psychotic drugs as well as psychedelic drugs.












Lewis was found dead in September in the driveway of a Los Angeles residence, and police found his landlady and a cat dead inside the home. Officials believe Lewis fell while trying to flee the home after killing 81-year-old Catherine Davis.


The killing occurred just days after Lewis was released from jail. Records show he had pleaded no contest to assault with a deadly weapon and attempted burglary in separate cases.


Authorities expressed concern about his mental health in court hearings before his release.


Entertainment News Headlines – Yahoo! News


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Clearing the Fog Around Personality Disorders





For years they have lived as orphans and outliers, a colony of misfit characters on their own island: the bizarre one and the needy one, the untrusting and the crooked, the grandiose and the cowardly.




Their customs and rituals are as captivating as any tribe’s, and at least as mystifying. Every mental anthropologist who has visited their world seems to walk away with a different story, a new model to explain those strange behaviors.


This weekend the Board of Trustees of the American Psychiatric Association will vote on whether to adopt a new diagnostic system for some of the most serious, and striking, syndromes in medicine: personality disorders.


Personality disorders occupy a troublesome niche in psychiatry. The 10 recognized syndromes are fairly well represented on the self-help shelves of bookstores and include such well-known types as narcissistic personality disorder, avoidant personality disorder, as well as dependent and histrionic personalities.


But when full-blown, the disorders are difficult to characterize and treat, and doctors seldom do careful evaluations, missing or downplaying behavior patterns that underlie problems like depression and anxiety in millions of people.


The new proposal — part of the psychiatric association’s effort of many years to update its influential diagnostic manual — is intended to clarify these diagnoses and better integrate them into clinical practice, to extend and improve treatment. But the effort has run into so much opposition that it will probably be relegated to the back of the manual, if it’s allowed in at all.


Dr. David J. Kupfer, a professor of psychiatry at the University of Pittsburgh and chairman of the task force updating the manual, would not speculate on which way the vote might go: “All I can say is that personality disorders were one of the first things we tackled, but that doesn’t make it the easiest.”


The entire exercise has forced psychiatrists to confront one of the field’s most elementary, yet still unresolved, questions: What, exactly, is a personality problem?


Habits of Thought


It wasn’t supposed to be this difficult.


Personality problems aren’t exactly new or hidden. They play out in Greek mythology, from Narcissus to the sadistic Ares. They percolate through biblical stories of madmen, compulsives and charismatics. They are writ large across the 20th century, with its rogues’ gallery of vainglorious, murderous dictators.


Yet it turns out that producing precise, lasting definitions of extreme behavior patterns is exhausting work. It took more than a decade of observing patients before the German psychiatrist Emil Kraepelin could draw a clear line between psychotic disorders, like schizophrenia, and mood problems, like depression or bipolar disorder.


Likewise, Freud spent years formulating his theories on the origins of neurotic syndromes. And Freudian analysts were largely the ones who, in the early decades of the last century, described people with the sort of “confounded identities” that are now considered personality disorders.


Their problems were not periodic symptoms, like moodiness or panic attacks, but issues rooted in longstanding habits of thought and feeling — in who they were.


“These therapists saw people coming into treatment who looked well put-together on the surface but on the couch became very disorganized, very impaired,” said Mark F. Lenzenweger, a professor of psychology at the State University of New York at Binghamton. “They had problems that were neither psychotic nor neurotic. They represented something else altogether.”


Several prototypes soon began to emerge. “A pedantic sense of order is typical of the compulsive character,” wrote the Freudian analyst Wilhelm Reich in his 1933 book, “Character Analysis,” a groundbreaking text. “In both big and small things, he lives his life according to a preconceived, irrevocable pattern.”


Others coalesced too, most recognizable as extreme forms of everyday types: the narcissist, with his fragile, grandiose self-approval; the dependent, with her smothering clinginess; the histrionic, always in the thick of some drama, desperate to be the center of attention.


In the late 1970s, Ted Millon, scientific director of the Institute for Advanced Studies in Personology and Psychopathology, pulled together the bulk of the work on personality disorders, most of it descriptive, and turned it into a set of 10 standardized types for the American Psychiatric Association’s third diagnostic manual. Published in 1980, it is a best seller among mental health workers worldwide.


These diagnostic criteria held up well for years and led to improved treatments for some people, like those with borderline personality disorder. Borderline is characterized by an extreme neediness and urges to harm oneself, often including thoughts of suicide. Many who seek help for depression also turn out to have borderline patterns, making their mood problems resistant to the usual therapies, like antidepressant drugs.


Today there are several approaches that can relieve borderline symptoms and one that, in numerous studies, has reduced hospitalizations and helped aid recovery: dialectical behavior therapy.


This progress notwithstanding, many in the field began to argue that the diagnostic catalog needed a rewrite. For one thing, some of the categories overlapped, and troubled people often got two or more personality diagnoses. “Personality Disorder-Not Otherwise Specified,” a catchall label meaning little more than “this person has problems” became the most common of the diagnoses.


It’s a murky area, and in recent years many therapists didn’t have the time or training to evaluate personality on top of everything else. The assessment interviews can last hours, and treatments for most of the disorders involve longer-term, specialized talk therapy.


Psychiatry was failing the sort of patients that no other field could possibly help, many experts said.


“The diagnoses simply weren’t being used very much, and there was a real need to make the whole system much more accessible,” Dr. Lenzenweger said.


Resisting Simplification 


It was easier said than done.


The most central, memorable, and knowable element of any person — personality — still defies any consensus.


A team of experts appointed by the psychiatric association has worked for more than five years to find some unifying system of diagnosis for personality problems.


The panel proposed a system based in part on a failure to “develop a coherent sense of self or identity.” Not good enough, some psychiatric theorists said.


Later, the experts tied elements of the disorders to distortions in basic traits.


This article has been revised to reflect the following correction:

Correction: November 29, 2012

An earlier version of this article misstated the number of traits included in the proposed criteria for narcissistic personality disorder.   The final proposal relies on two personality traits, not four.



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DealBook: Vinod Khosla Keeps Long-Term Bet on Clean Technology

Vinod Khosla crowed about the clean energy industry last year. Three of the biofuel start-ups in his venture capital portfolio had just gone public, and the stocks had risen considerably after their debuts. “I challenge anybody to claim that clean tech done right is a disaster,” Mr. Khosla said at a conference, rebuffing recent criticism. “We’ve generated more profits there than anybody has.”

Since then, Mr. Khosla, the founder of Khosla Ventures, has watched much of those paper gains evaporate. As the clean energy industry broadly has taken a hit, shares of the biofuel companies — Amyris, Gevo and KiOR — have slumped 70 percent to 90 percent from their peaks. His stakes, once worth as much as $1.3 billion, are now valued at roughly $378 million.

The billionaire investor has been caught in the cyclical downdraft.

The public stocks of solar, wind and biofuel companies are suffering amid industrywide pressures. The price of natural gas remains low. Europe has pulled back on incentives. American subsidies are in question after the bankruptcy of the solar panel maker Solyndra. And China is providing formidable low-cost competition.

“The whole clean tech sector has been out of favor,” said Pavel Molchanov, an analyst at Raymond James & Associates, a brokerage firm. “I’d be hard pressed to name one trading above its I.P.O. price.”

Despite the crosscurrents, Mr. Khosla seems unwavering in his commitment. He is pouring money into start-ups. Khosla Ventures recently invested more in LightSail Energy, a three-year-old start-up working to develop low-cost energy storage. He is also sticking with his public companies. His firm, for example, still owns 54 percent of KiOR.

“He’s a visionary who likes to make big bets on ideas that can really change the world,” said Andy Bechtolsheim, who co-founded Sun Microsystems with Mr. Khosla 30 years ago and shares a house with him at Big Sur on the California coast. “I would think he’s made a larger personal bet on green tech than anybody else.”

While the public markets are raising short-term doubts, the long-term investment thinking remains unchanged. Governments around the globe are pushing to find alternative sources of energy in an effort to reduce their dependence on fossil fuels that may hurt the environment. In a television interview in 2007, Mr. Khosla said “mainstream solutions” could replace up to 80 percent of oil-based power. Without them, he said, “this planet is history the way we know it today.” After Hurricane Sandy, the subject of global warming — and changing climate conditions — has again come to the forefront.

In a recent blog post on the Forbes Web site, Mr. Khosla acknowledged the shift in market sentiment. “Clean tech went through a time when it was in vogue and now it is not,” he wrote. “The financing environment for clean tech companies is tough today,” he added. But he said he still expected “to do better than industry averages by keeping our losing companies to a minority.”

Since founding his venture capital firm in 2004, Mr. Khosla has become one of the most vocal advocates for clean tech innovation, buying stakes in about 60 industry start-ups. Ausra, a solar thermal start-up that had drawn $130 million in venture backing, was sold in 2010 to the French nuclear plant builder Areva for about $250 million, according to one industry estimate. And SeaMicro, a low-power server maker, was bought this year by Advanced Micro Devices for $334 million, more than five times the amount invested by its venture backers, according to a SeaMicro co-founder, Andrew Feldman.

It’s unclear how the broader clean tech portfolio has performed at Khosla Ventures. Mr. Khosla declined to disclose the firm’s returns or to comment for the article.

But one of his funds, which raised $1 billion to invest in clean tech and other start-ups, shows gain of 30 percent since its inception in 2009, according to filings by the California Public Employees’ Retirement System, the largest state pension fund. In his Forbes blog post, Mr. Khosla said a recent fund, which raised $1.05 billion in October 2011, was oversubscribed, and his firm’s broader performance since 2006 had “well exceeded typical venture funds.” In that period, venture funds over all have returned 7.25 percent annually after fees, according to industry data.

Mr. Khosla’s commitment is an outgrowth of his three decades at the cutting edge of technology.

A native of India, Mr. Khosla, 57, earned a master’s degree in biomedical engineering from Carnegie Mellon and an M.B.A. from Stanford in 1980. After starting the design automation company Daisy Systems in 1982, he co-founded Sun Microsystems, then a growing technology company.

At Sun, he supplied drive and vision. But Mr. Khosla, who is known for his blunt talk and intense manner, was replaced as chief executive two years later and left the company shortly thereafter.

In 1986, he joined the venture capital firm Kleiner Perkins Caufield & Byers. Over the next two decades, Mr. Khosla scored sizable returns betting on the growth of fiber optic networks. Two companies, Cerent and Siara Systems, were sold for a combined $15 billion-plus at the height of the late-1990s dot-com bubble.

Mr. Khosla was looking into alternative fuel technologies at Kleiner Perkins when a business plan for an ethanol start-up crossed his desk in 2003. The plan “sat on a corner of my desk for nearly 18 months while I read everything I could about petroleum and its alternatives,” he wrote in an article for Wired magazine in 2006.

When he branched out on his own in 2004, Mr. Khosla invested millions in the ethanol start-up, Celunol. He soon established himself as a top venture capitalist in clean tech, attracting prominent outside investors like Microsoft’s founder, Bill Gates. Former Prime Minister Tony Blair of Britain joined the firm as a senior adviser.

Over the years, Mr. Khosla has experienced his share of blowups.

In September 2011, Khosla-backed Range Fuels, a wood-chips-to-ethanol company, went bankrupt after receiving a $44 million grant from the Department of Energy and $33 million under a Department of Agriculture loan guarantee. When The Wall Street Journal editorial page criticized Range Fuels as an “exercise in corporate welfare,” Mr. Khosla lashed back, saying the authors inhabited an “ivory tower” that was “full of people who don’t understand technology.”

Sometimes, Mr. Khosla’s companies had to pivot from their original plans and focus on new markets. For example, Calera was founded in 2007 with plans to use power plant exhaust to make cement. Mr. Khosla called its technology “game changing” in 2008.

But the company encountered some setbacks. It postponed plans for commercial-scale production in 2010 pending further research and later cut its 145-employee work force by two-thirds. Since then, Calera has broadened its focus, developing other products like fillers for paper and plastics.

Like many venture capital investors, Mr. Khosla will risk a few strikeouts for the chance to hit home runs. “My willingness to fail is what gives me the ability to succeed,” the investor has said frequently.

The odds can be especially brutal in clean technology. The projects are often capital-intensive — like $200 million or more for a biofuels plant — and they can take years to pay out, said Sam Shelton, a research engineer at Georgia Institute of Technology. By comparison, social media start-ups often require little upfront money and few employees. “The economics are totally different,” Mr. Shelton said.

In part, Mr. Khosla aims to take stakes when the companies are still getting off the ground, rather than waiting until they’re more mature and more expensive. He first bought a stake in KiOR, which aims to convert wood chips to gas and diesel fuel, in 2007. The company is now completing the first of five planned plants in Mississippi with the help of a $75 million interest-free loan from the state.

Mr. Khosla is “always thinking at a very high level about the potential of an idea,” KiOR’s chief executive, Fred Cannon, said. “He has a very good feel for when to step on the gas.”

After jumping in early, Mr. Khosla appears willing to ride out the swings, in both directions. Over the years, public filings indicate he has plowed roughly $80 million into KiOR, amassing a 54 percent stake in the company. Although the stock is off its peak levels and I.P.O. investors are still underwater, his holdings are worth $356 million — a threefold gain.


This post has been revised to reflect the following correction:

Correction: November 30, 2012

An earlier version of this article mischaracterized Mr. Khosla's return on his investment in KiOR. He invested roughly $80 million and his holdings are worth $356 million — a threefold gain, not a fourfold gain.

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